delta.calculate         Calculates the rank-based test statistic for Y
                        and S and the difference, delta
delta.calculate.extension
                        Calculate Delta: Difference in Rank-based
                        Statistics for Two Outcomes
delta.reml.meta         Function to perform meta-analysis of summary
                        statistics and hypothesis testing for a single
                        marker
est.power               Estimated power to detect a valid surrogate
example.data            Example data
example.data.highdim    High‑dimensional surrogate candidate example
                        dataset
example.data.highdim.multistudy
                        High-dimensional, multi-study surrogate
                        candidate example dataset
example.data.highdim.multistudy.ipd
                        High‑dimensional multi-study individual
                        participant surrogate candidate example dataset
generate.example.data.highdim
                        Generate individual participant data for
                        high-dimensional surrogate candidates and
                        response
generate.example.data.highdim.multistudy
                        Generate high-dimensional multi-study surrogate
                        marker trial-level effects
generate.example.data.highdim.multistudy.ipd
                        Generate multi-study individual participant
                        data for high-dimensional surrogate candidates
                        and response
rise.evaluate           Function to perform the evaluation stage of
                        RISE : Two-Stage Rank-Based Identification of
                        High-Dimensional Surrogate Markers
rise.evaluate.meta      Function to perform the evaluation stage of
                        RISE-meta : Meta-Analysis of High-Dimensional
                        Surrogate Markers
rise.screen             Function to perform the screening stage of RISE
                        : Two-Stage Rank-Based Identification of
                        High-Dimensional Surrogate Markers
rise.screen.meta        Function to perform the screening stage of
                        RISE-meta : Meta-Analysis of High-Dimensional
                        Surrogate Markers
test.surrogate          Tests whether the surrogate is valid
test.surrogate.extension
                        Function to test for trial-level surrogacy of a
                        single marker extended to the paired, two sided
                        test setting
test.surrogate.rise     Function to perform RISE : Two-Stage Rank-Based
                        Identification of High-Dimensional Surrogate
                        Markers
